While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners. "Hydrochloroquine (Plaquenil) has been a blessing for me. Chloroquine mechanism of action ppt Is hydroxychloroquine safe while pregnant Chloroquine endocytosis inhibitor Surgery while taking plaquenil Plaquenil might affect the eyes, the retina, why those of us taking Plaquenil are followed by an ophthalmologist and also have visual field tests every 6 months or once a year. If there are changes, then Plaquenil is stopped. Like bubbles wrote, Plaquenil stays in the body for a while. Has your friend's doctor discussed other meds to take? Call your doctor right away if you notice any of these side effects Blurred vision or changes in your vision. Convulsions, seizures, or other neurological symptoms these are very rare. Muscle aches or weakness. Nervousness or anxiety. Headaches. Withdrawal syndrome is found among people who take Plaquenil, especially for people who are female, 50-59 old also take medication Lyrica, and have Fibromyalgia. This study is created by eHealthMe based on reports of 48,911 people who have side effects when taking Plaquenil from Food and Drug Administration FDA, and is updated regularly. I do occasionally experience dry eyes and a little scalp itch but asserting that it's caused by Hydrochloroquine would be anecdotal at best. It took about 5 weeks to take effect but my RA is basically a non factor now. Plaquenil stopped working Plaquenil and nerve damage - Scleroderma - Inspire, Plaquenil Hydroxychloroquine for Lupus - LupusCorner Quinolone and chloroquine resistance developmentChloroquine colon cancerTest done before plaquenilAf plaquenil I have read about people stopping P & flaring up. Those who stopped it abruptly had real problems similar to what you are experiencing. If you really need to get off it, I would taper down slowly, very slowly. There is a similar posting on Healthunlocked, "Why oh why did u stop taking plaquenil." You may want to check it out. Hydroxychloroquine plaquenil withdrawl? - LUPUS UK. Will you have Withdrawal syndrome with Plaquenil - eHealthMe. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. Plaquenil is generally well-tolerated, but side effects are possible. Common side effects linked to Plaquenil include nausea and diarrhea. Taking the medication with food eases nausea for most people taking the drug. Less common side effects include skin rashes, hair thinning, and weakness. Plaquenil hydroxychloroquine "Used plaquenil for 6 weeks until I developed a terrible full-body rash. It was working for the inflammation and pain very well until the rash" It was working for the inflammation and pain very well until the rash" If your ophthalmologist does find some Plaquenil deposits, s/he will simply request that you stop taking the medication, and you may follow up with your rheumatologist about another advised method of treatment. Unfortunately, retinal damage caused by Aralen may be irreversible, but this medication is rarely prescribed anymore for lupus.