If the disease affects your mucous membranes, it tends to be more resistant to treatment and prone to recur. Whatever treatment you use, you'll need to visit your doctor for follow-up appointments about once a year. How long should you take hydroxychloroquine Plaquenil for spondyloarthritis Chloroquine resistance development LICHEN PLANUS LP is a well-characterized dermatological condition affecting the skin, mucosa, hair, and nails, but its treatment is often disappointing and controversial. Various drugs or physical treatments have been proposed in the past 30 years, but the majority of these reports consist of small series of patients or anecdotes. Lichen planopilaris LPP is a primary lymphocytic scarring alopecia that causes inflammation, erythema, pruritus, dysesthesia, and alopecia that can be treatment resistant. After approval from the institutional review board, we performed a retrospective case analysis of alopecia due to LPP to. A variety of systemic agents are used to treat lichen planopilaris LPP with a limited evidence base. The aim of our study was to retrospectively review the response rate to and tolerability of hydroxychloroquine in a cohort of patients with LPP in an effort to add to the evidence base for its use. The first choice for treatment of lichen planus is usually a prescription corticosteroid cream or ointment. Medications and other treatments might help relieve itching, ease pain and promote healing. Talk with your doctor to weigh the potential benefits against possible side effects of treatment. Lichen planopilaris treatment hydroxychloroquine User Reviews for Hydroxychloroquine to treat. -, Lichen Planopilaris Retrospective Study and Stepwise. Plaquenil skinHydroxychloroquine lymphadenopathy BACKGROUND Lichen planopilaris LPP and its variant frontal fibrosing alopecia FFA are primary lymphocytic cicatricial alopecias for which there is no evidence-based therapy. OBJECTIVE We assessed the efficacy of hydroxychloroquine in active LPP and FFA using the LPP Activity Index LPPAI, a numeric score that allows quantification of the. Hydroxychloroquine and lichen planopilaris efficacy and.. The role of hydroxychloroquine in the treatment of lichen.. Lichen planopilaris - UpToDate. Hydroxychloroquine is considered safer than chloroquine during pregnancy and lactation. Hydroxychloroquine is rapidly absorbed from the gastrointestinal tract, and steady-state concentrations are reached after 4–6 weeks; 45% of hydroxychloroquine binds to plasma proteins that are deposited in tissues such as the liver, spleen, kidney, and lung. Lichen Planopilaris LPP is a form of scarring alopecia and is a rare inflammatory condition that results in patchy permanent hair loss on the crown and vertex. It destroys the hair follicle and replaces it with scarring. Symptoms can include an intensely itchy scalp and scalp tenderness. LPP is considered a follicular form of Lichen Planus. Lichen planopilaris LPP, a follicular form of lichen planus, is a rare inflammatory lymphocyte mediated disorder. Although the physiopathology is unclear, an autoimmune etiology is generally.