There’s no cure for arthritis, which is unfortunate, but feeling better is definitely possible. The progression of RA may be diminished in severity and duration by the combination of medicines and therapy that work best as determined by you and your physician. Plaquenil drug information Hydroxychloroquine rxnorm code Plaquenil icd 9 Plaquenil drug guide Hydroxychloroquine is a one of a number of drugs which have been used for many years in the treatment of malaria. Fortunately, it was discovered these drugs often are helpful in the treatment of various rheumatic diseases, particularly systemic lupus erythematosus SLE or "Lupus" and rheumatoid arthritis. I started Plaquenil 2 months ago. My Rheumatologist told it can up to 3 months to start working. Be very careful with plaqenil. Yes, it was great for the pain but I bloated up and put on a great deal of weight very quickly. Plaquenil hydroxychloroquine is an antimalarial medication used to treat or prevent malaria, a disease caused by parasites, which enter the body through the bite of a mosquito. Plaquenil is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Being able to stop joint damage can lessen pain and mean a better quality of life. You can also put off joint damage, and in some cases, you can do more than just slow it down. When does plaquenil start working Hydroxychloroquine Plaquenil, Plaquenil - HealthBoards Plaquenil taken with uroxatralPlaquenil and steroidsIs plaquenil a fluoroquinoloneWhat medicines are ok to take with hydroxychloroquine For patients taking hydroxychloroquine to prevent malaria Your doctor may want you to start taking this medicine 1 to 2 weeks before you travel to an area where there is a chance of getting malaria. This will help you to see how you react to the medicine. Hydroxychloroquine Oral Route Proper Use - Mayo Clinic. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. How long until Plaquenil started working?. Last week my doc added plaquenil to the mix. I have a pharmacist friend that says it can take up to a year to work, but once its kicks in it can be really good. I suggest you ask your rhuemie for additional help in the meantime. I have had RA going on 12 years, and originally way back when I ws given plaquenil alone and it did nothing. Does Plaquenil actually work for you? I never actually noticed a difference when I was taking Plaquenil long-term. A few years ago, when I stuck to a super healthy diet, I actually noticed a difference in my symptoms, so I stopped taking Plaquenil. Depending on how full your stomach it codine should take 20 min to a hour to work.