Chloroquine is now uncommonly used in favor of its derivative hydroxychloroquine. In the United States, hydroxychloroquine is most often used for its anti-inflammatory effects in rheumatology and dermatology. Can you get high off hydroxychloroquine 200 mg Drugs used to treat chloroquine resistant malaria Plaquenil equivalent Is hydroxychloroquine safe to take while breastfeeding Hydroxychloroquine sulfate HCQ, Plaquenil is an analogue of chloroquine CQ, an antimalarial agent, used for the treatment of systemic lupus erythematosus, rheumatoid arthritis and other autoimmune disorders. Its use has been associated with severe retinal toxicity, requiring a discontinuation of therapy. Hydroxychloroquine is a commonly used medication for rheumatoid arthritis, systemic lupus erythematosus, discoid lupus, Sjögren syndrome, juvenile idiopathic arthritis, other mixed connective tissue autoimmune conditions, non-small cell lung cancer, and graft-versus-host disease GVHD, to name a few. Combining the results of examinations, HCQ retinal toxicity was deter-mined by 1 ophthalmologist, an expert in retinal diseases. The pattern of retinal toxicity was described as a parafoveal pattern, pericentral pattern, or mixed pattern of retinal toxicity, according to the location of retinal damage. While early toxicity may be asymtomatic, patients with more advanced stage of toxicity may complain of color vision changes or paracentral scotomas. Its toxic effects on the retina are seen in the macula. Hydroxychloroquine retinal toxicity retina replacement Hydroxychloroquine toxicity - EyeWiki, Determine risk for hydroxychloroquine retinal toxicity. Lc3 aging gapdh chloroquine heartChloroquine drug infoDoes prednisone and plaquenil work for ankylosing spondylitis On examination, a telltale sign of hydroxychloroquine toxicity is a bilateral change in the retinal pigment epithelium of the macula that gives the commonly described appearance of a bull’s-eye. This is a late finding, however, and too late for screening to be useful. Hydroxychloroquine-Induced Retinal Toxicity - American.. Risk of Retinal Toxicity in Longterm Users of.. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. Lyons emphasizes the importance of annual screening and says that, although annual screening is recommended for everyone taking Plaquenil, it is imperative for people who have been taking the medication for more than 10 years, who have a higher incidence of retinal toxicity. Retinal Toxicity Associated With Hydroxychloroquine and Chloroquine Risk Factors, Screening, and Progression Despite Cessation of Therapy Article in Archives of ophthalmology 129130-9. Topiramate Topamax is used to treat epilepsy and migraines. The drug also is used off-label for a number of concerns, including weight loss, bipolar disorder and depression. It has been associated with acute angle-closure glaucoma and transient myopia. Statins may be associated with diplopia.