Moreover, it is used as an adjunct in chemotherapy, and it is being investigated as a treatment for diabetes and heart disease, thanks to its anti-inflammatory, lipid-lowering, and antithrombotic properties. But as ophthalmologists know, excessive HCQ dosages can result in toxic damage to the eye. Abatacept sulfasalazine hydroxychloroquine triple therapy Plaquenil with ldn Benefits of plaquenil for lupus My Take on New Ocular Screening Guidelines for Plaquenil By Sergio Schwartzman, MD 12 October 2016. A recent article published by the American Academy of Ophthalmology AAO presented new recommendations for screening of patients being managed with hydroxychloroquine HCQ. In this article, new recommendations were made that changed the. There are guidelines on the amount of Plaquenil a person should be able to take safely in a lifetime, and Katz encourages those taking the medication to discuss this with their ophthalmologists. “I think there are some people, like Ann, whose bodies, for whatever reason, don’t metabolize drugs as well,” he says. Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Highlights of the 2016 guidelines include the following. “The bottom line is that the daily dose should be 5.0 mg per kg or less, using real body weight,” said Michael F. In an effort to reduce the incidence of HCQ retinopathy, the Academy published screening guidelines in 2002. Here’s an overview of the latest guidelines—and troubling evidence that far too many patients are still receiving too high a dose of HCQ (see “Excessive Dosing Still a Problem,” below). Hydroxychloroquine guidelines Drug spotlight on hydroxychloroquine Lupus Foundation of., Protecting your eyesight when taking Plaquenil Lupus. Chloroquine lc3-iiFda warning sandoz hydroxychloroquine Adult dosage and administration A typical dose may be 200 - 400mg daily 400mg should be given in divided doses. Total daily dose should not exceed 6.5mg/kg/day based on ideal body weight. Hydroxychloroquine - IPNSM. Hydroxychloroquine Plaquenil. Hydroxychloroquine MedlinePlus Drug Information. How to use Hydroxychloroquine SULFATE. Hydroxychloroquine is usually taken with food or milk to prevent stomach upset. The dosage and length of treatment are based on your medical condition and response to therapy. In children, dosage is also based on weight. Generally, hydroxychloroquine is given in 200 mg or 400 mg doses, once per day. Higher doses can sometimes be used, but only in adults and not for all cases. Some people tolerate this medication much better than other people, so it is important that individuals who are considering taking hydroxychloroquine talk with their doctor about the lowest necessary dose to reduce or eliminate their symptoms. Previous 30 recommendations by the AAO to limit HCQ dosing to 6.5 mg/kg of ideal body weight have been 31 revised to 5 mg/kg of actual body weight 5. Some authors recommend 6.5 mg/kg of actual 32 body weight with a cap at 400 mg per day and further adjustments for renal insufficiency 10.