Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Side effects of hydroxychloroquine tablets 200 mg Les éffets secondaires de plaquenil au long cours Plaquenil ingredients Jan 05, 2020 Hydroxychloroquine Plaquenil and chloroquine cause ocular toxicity to various parts of the eye such as the cornea, ciliary body, and retina. Chloroquine can also induce cataract formation; however, no reports of hydroxychloroquine and cataract have been reported 1. Oct 01, 2012 It is reported that 10–25% of patients treated with antimalarial drugs experience cutaneous hyperpigmentation. However, most reports have described chloroquine‐induced hyperpigmentation, and hyperpigmentation due to hydroxychloroquine has been rarely reported. We herein report a case of hydroxychloroquine‐induced hyperpigmentation. Hydroxychloroquine Plaquenil® is a 4-amino-quinoline antimalarial medication that is widely used to treat systemic lupus erythematosus SLE, rheumatoid arthritis, and related inflammatory and dermatological conditions. It is a hydroxylated version of chloroquine, with a similar mechanism of action. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Plaquenil hydroxychloroquine hyperpigmentation Systemic Scleroderma Skin Involvement Hyperpigmentation and., Hydroxychloroquine‐induced hyperpigmentation, The Journal of. Natural substitute for plaquenilRheumatoid arthritis methotrexate therapy hydroxychloroquine monotherapyPlaquenil tylenolChloroquine phosphate powder lethal Aug 18, 2011 Plaquenil or hydroxychloroquine has been known to cause a darkened discoloration of skin and/or mucous membranes. This is considered an adverse reaction and should be discussed with your prescriber. It is important to evaluate this color change to make sure there is nothing else wrong. Skin Discoloration and Plaquenil - Arthritis Information. Hydroxychloroquine DermNet NZ. Hydroxychloroquine‐induced hyperpigmentation the staining.. Hydroxychloroquine hye-drox-ee-klor-oh-kwin Plaquenil Classiﬁcation. bleaching of hair, alopecia, hyperpigmentation, photosensitivity, Stevens-Johnson Feb 19, 2020 Hydroxychloroquine sulfate is a colorless crystalline solid, soluble in water to at least 20 percent; chemically the drug is 2-4-7-Chloro-4-quinolylaminopentylethylamino ethanol sulfate 11. PLAQUENIL hydroxychloroquine sulfate tablets contain 200 mg hydroxychloroquine sulfate, equivalent to 155 mg base, and are for oral administration. Hydroxychloroquine is converted to an inactive metabolite in the liver and excreted in urine 25% in the active form and bile. The plasma half-life is 32-50 days. Although some of the pigmentary effects are known to be dose dependent, in most cases dyschromia does not appear to be related to cumulative doses 7.