Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Mucinex and plaquenil Plaquenil oct findings Hydroxychloroquine azathioprine gout medications How do i get off the drug plaquenil Plaquenil side effects Get emergency medical help if you have signs of an allergic reaction to Plaquenil hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Taking Plaquenil long-term or at high doses may cause irreversible damage to the retina of your eye. The crazy thing about this itching is that this is the 3rd attempt back on the plaquenil and with the 1st two tries I had no itching but different side effects that made me discontinue it. The 1st time I was on it brand name 400 mg. for 8 months and had to d/c due to terrible intestinal cramping and tinnitus. According to Drugs.com, Plaquenil given for a long term can cause retinal disorders after a few months or years of daily use--especially if the dose exceeds 400mg per day. The risk of retinal damage increases at doses of 600mg to 700mg. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. How long do side effects of plaquenil last Let me tell you what weaning down from Plaquenil is like., Terrible Itching on Plaquenil---PLEASE HELP. Plaquenil aseptic meningitisPlaquenil lucite polymorphe Hydroxychloroquine Plaquenil is used to treat malaria, lupus, and rheumatoid arthritis. Learn about side effects, warnings, dosage, and more. Hydroxychloroquine Side Effects, Dosage, Uses, and More. Long-Term Side Effects of Plaquenil for Rheumatoid.. Plaquenil Side Effects Go Away? DailyStrength. What are the side effects of Plaquenil? The most common side effects are diarrhea, nausea, vomiting, headache, dizziness, skin rash or black spots when you look at things. Most side effects will go away when your body gets used to the medicine. Tell your doctor if you have these side effects. A lower dose may stop them. Do not lower the dose on. RARE side effects. If experienced, these tend to have a Severe expression. Abnormal Liver Function Tests. Acute Liver Failure. Acute Pustular Eruptions On Skin. Bronchospasm. Decreased Blood Platelets. Decreased White Blood Cells. When I increased to 200mg/day, I had strange side effects that caused me to go back to 100/day. Strange leg cramping, restless leg, nausea and anxiety. In a nutshell, at 200mg/day the side effects outweighed the benefits. At 100mg/day, I do not have 100% reduction in my symptoms, but I have enough of a reduction to want to continue the.