PLAQUENIL film-coated tablets cannot be divided, therefore they should not be used to treat patients who weigh less than 31 kg. For radical cure of The recommended adult dosage is 200 to 400 mg (155 to 310 mg base) daily, administered as a single daily dose or in two divided doses. The incidence of retinopathy has been reported to be higher when this maintenance dose is exceeded. Can hydroxychloroquine cause staphylococcus aureus uti Can plaquenil cause bad teeth Because early toxicity changes can be revealed on SD-OCT, it is prudent to perform a baseline screening of patients taking Plaquenil. Multifocal ERG has the ability to detect early macular dysfunction, so it should be included as part of baseline screening. A maximum daily dose of Plaquenil of 5.0mg/kg real weight is recommended. Revised Guidelines For Plaquenil Screening. Amsler grids are no longer recommended by the Academy- use 10-2 visual fields. Also, OCT to detect parafoveal retinal thinning, mERG and fundus autofluorescence are useful. Annual screening should begin after 5 years or sooner if there are unusual risk factors. SCREENING TESTS Newer objective tests, such as multifocal electroretinogram mfERG, spectral domain optical coherence tomography SD-OCT, and fundus autofluorescence FAF, can be more sensitive than visual fields. In a small percentage of patients, side effects may require temporary reduction of the initial dosage. 400 mg to 600 mg (310 to 465 mg base) daily, administered as a single daily dose or in two divided doses. New plaquenil screening guidelines Hydroxychloroquine Plaquenil Toxicity and Recommendations., New guidelines issued for plaquenil screening Can plaquenil cause itchy skin Sep 23, 2015 Patients starting chloroquine CQ or hydroxychloroquine HCQ; i.e. Plaquenil should have a baseline examination that serves as a reference point, as well as to rule out any preexisting maculopathies. Quick Reference Screening for Chloroquine.. Revised recommendations on screening for chloroquine and.. New Guidelines on Hydroxychloroquine Dosage - Where Are We.. The AAO published dosing and screening recommendations for chloroquine and hydroxychloroquine in 2016, revising previous recommendations published in 2011. The current maximum daily HCQ dose. Recommendations on Screening for Chloroquine and Hydroxychloroquine Retinopathy Retinal toxicity from chloroquine CQ and its analogue, hydroxychloroquine HCQ, has been recognized for many years. Chloroquine toxicity remains a problem in many parts of the world, but is seen less frequently in the United States where the drug largely has been replaced by HCQ. Background The American Academy of Ophthalmology recommendations on screening for chloroquine CQ and hydroxychloroquine HCQ retinopathy are revised in light of new information about the.