One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine (Plaquenil), a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus. Can you take plaquenil with lipitor Hydroxychloroquine plaquenil drug class Chloroquine drug info Tell your doctor immediately if any of these rare but very serious side effects occur severe stomach/abdominal pain, severe nausea/vomiting, easy bleeding/bruising, signs of infection e.g. fever, persistent sore throat, seizures, shortness of breath, swelling ankles/feet, extreme tiredness, dark urine, yellowing eyes/skin. Dronedarone Severe Dronedarone administration is associated with a dose-related increase in the QTc interval. The increase in QTc is approximately 10 milliseconds at doses of 400 mg twice daily the FDA-approved dose and up to 25 milliseconds at doses of 1600 mg twice daily. Show Full Comment Comment This medication relieved my joint pain, muscle weakness, myositis, pleuritic pain, and fatigue after about 2-3 months of starting the medication. It is imperative that patients and physicians are aware of and watch for this drug’s ocular side effects. Retinal toxicity from hydroxychloroquine is rare, but even if the medication is discontinued, vision loss may be irreversible and may continue to progress. Plaquenil ful fielderg severe PLAQUENIL Side Effects, Reviews by Patients -, Plaquenil hydroxychloroquine sulfate dose, indications. Plaquenil and valium Hydroxychloroquine, sold under the brand name Plaquenil Sanofi-Aventis, is an antimalarial drug that has gained widespread use in treating various autoimmune diseases, including systemic lupus erythematosus and rheumatoid arthritis. 1 By some estimates, more than 150,000 patients are on long-term therapy with this medication in America alone. 2 Retinal toxicity associated with HCQ use is. Multimodal Imaging in Plaquenil Toxicity. Plaquenil oral Reviews and User Ratings Effectiveness, Ease.. Retinal toxicity to antimalarial drugs chloroquine and.. A total of 226 drugs are known to interact with Plaquenil, including 8 major drug interactions. For a full list that can be easily searched, visit You should avoid taking antacids or Kaopectate within 4 hours of taking Plaquenil. Some antacids may make it harder for your body to absorb the medication. Severe blood disorder such as aplastic anemia, agranulocytosis, leukopenia, or thrombocytopenia, appears which is not attributable to the disease under treatment, consider discontinuation of PLAQUENIL. Plaquenil is a slow-acting drug, meaning that it can take up to 6 months to experience the full benefits of this medication, but it is possible for symptoms to improve in as few as 1 or 2 months. Plaquenil and other antimalarials are the key to controlling lupus long-term, and some lupus patients may be on Plaquenil for the rest of their lives.