Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Plaquenil and 5hr energy interactions Plaquenil reduces preeclampsia Plaquenil dosage maculopathy Plaquenil is prescribed as a disease-modifier, in other words, to decrease pain, decrease swelling, and prevent joint damage and disability. It is not known how Plaquenil works but researchers believe that Plaquenil interferes with communication between cells within the immune system. Ultimately, it is thought to block proinflammatory. I saw the dentist today and I have to have a lot of dental work done. I read about Plaquenil and being careful about infection. Anyone have input on this. I guess you have a higher rate of getting an infection? I am 52 and they are also talking about extracting my wisdom teeth surgically. Note This document contains side effect information about hydroxychloroquine. Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Plaquenil and dental surgery Oral Problems and Concerns with People and Lupus. Everything., Plaquenil and dental work DailyStrength Plaquenil for saleHydroxychloroquine and live vaccines Plaquenil is also used in some circumstances to control arthritis and may result in a lichenoid reaction or rash on the inside of the mouth. Immunosuppressive medications such as cyclophosphamide or methotrexate may result in opportunistic bacterial infection which could compromise periodontaly involved teeth or dental implants. Oral Problems and Concerns with People and Lupus.. Plaquenil Side Effects Common, Severe, Long Term -. Plaquenil Oral Uses, Side Effects, Interactions, Pictures.. It may help if you see your lupus doctor before surgery to get a “medical clearance”. This clearance is a summary of your medical history, including recent lab tests, x-rays and electrocardiogram. Sometimes these tests have to be repeated before surgery. PDR Drug Summaries are concise point-of-care prescribing, dosing and administering information to help phsyicans more efficiently and accurately prescribe in their practice PDR's drug summaries are available free of charge and serve as a great resource for US based MDs, DOs, NPs and PAs in patient practice There are many risks of undergoing dental surgery while taking the drug Plaquenil. You can for example experience severe dizziness or drowsiness.