Increased sensitivity to sunlight is a side effect of many widely used prescription and over-the-counter drugs. Rapid and severe sunburns, hives, rashes and increased risk of skin cancer can result. Sle on plaquenil Plaquenil does it cause bone loss Plaquenil and breast cancer The sun causes lupus heat intolerance and that is caused by poor blood flow to the skin, lessening the ability to sweat. Sweating is a way that your body controls your temperature. Your Meds. Drugs that treat arthritis can increase your sensitivity. NSAIDs like Advil, naproxen, Celebrex; Plaquenil; Methotrexate and Azulfidine For example Plaquenil Your body then makes a chemical that causes the allergic reaction. So every time you are exposed to the allergan, the body makes the chemical very quickly as it now knows how and you get a rash, or other symptoms. This post may contain affiliate links, to find out more information, please read my disclosure statement. As well as cold intolerance, where you can be extremely sensitive to cold temperatures, heat intolerance can be a symptom of thyroid disease, too. Assorted antibiotics, sulfa drugs, cold and allergy medicines and pain killers are among the medications that can make people more vulnerable to sun and heat. Increased sensitivity to heat, which can lead to dehydration, is also a side effect of many common medications. Plaquenil and heat intolerance Rheumatoid Arthritis 17 Signs of Serious Complications, Allergic reaction to plaquenil DailyStrength Hydroxychloroquine renal dosingSide effects plaquenil forumsEfectos secundarios de plaquenil I Had to go off of plaquenil due to severe heat intolerance after being on it almost a year. I had near heat stroke last summer and I could not even tolerate a warm building without almost passing out. I am seeing a new rheumy in a few weeks and was wondering what he might put me on instead. Instead of plaquenil?. Heat Intolerance and Thyroid Disease. Buying Plaquenil - Brand & Generic Plaquenil Canada Drugs. Sep 11, 2014 Photosensitivity is a common side-effect of methotrexate, plaquenil, and NSAIDs such as celebrex or advil. Photosensitivity may also be a serious side-effect of anti-TNF drugs such as cimzia, enbrel, humira, remicade, and simponi, as well as sulfasalazine. Also called Heat Intolerance, it usually signifies a need for a person to wear unusually light clothing for a given air temperature. Typically used to describe symptoms in people with an overactive thyroid gland who experience an elevation in their basal body temperature. Heat and humidity intolerance. Summer heat brings on a flare, not just the sun. Sudden heat like getting into a hot automobile that has been in the sun with windows rolled up. One blast of heat and I have had a flare. I have had flares in Walmart with all the lights.