Malaria parasites can enter the body through these mosquito bites, and then live in body tissues such as red blood cells or the liver. This medication is used to kill the malaria parasites living inside red blood cells. How do i get off the drug plaquenil Chloroquine mechanism of action iodine Plaquenil retinopathy pathogenesis Chloroquine is a 9-aminoquinoline known since 1934. Apart from its well-known antimalarial effects, the drug has interesting biochemical properties that might be applied against some viral infections. Chloroquine exerts direct antiviral effects, inhibiting pH-dependent steps of the replication of several viruses including members of the flaviviruses, retroviruses, and coronaviruses. Its best. Chloroquine can be used to treat porphyria cutanea tarda, but in a very low dose 125 mg twice weekly as a dosage of 250 mg/day can trigger a porphyria crisis, which can be fatal. Chloroquine is contraindicated where there is a known hypersensitivity to 4-aminoquinoline compounds. Chloroquine is therefore used widely for P. vivax, P. malariae and P. ovale, but except in a very few areas has been replaced for P. falciparum treatment. The time-honoured oral chloroquine regimen of 25 mg base/kg spread over 3 days 10, 10, 5 or 10, 5, 5, 5 mg/kg at 24-hour intervals can be condensed into 36 hours of drug administration. Both drugs may be needed for a complete cure and to prevent the return of infection (relapse). In some cases, you may need to take a different medication (such as primaquine) to kill the malaria parasites living in other body tissues. Regimens of chloroquine Chloroquine Oral Uses, Side Effects, Interactions, Pictures., Chloroquine DermNet NZ Chloroquine interfer nucleic acid biosynthesisChloroquine sketchyHydroxychloroquine and peripheral neuropathyChloroquine phosphate for saleHydroxychloroquine myositis The nurse will explain which of the following regimens of chloroquine prescribed by the physician? Taking the medication for 2 weeks before the trip and for 4 to 6 weeks after the trip. Which drug is currently the mainstay of antimalarial therapy? Chloroquine Aralen Chapter 12 quiz Flashcards Quizlet. Chloroquine - an overview ScienceDirect Topics. The pharmacokinetics of three multiple dose regimens of.. Efficacy of 3 Regimens of Chloroquine and Primaquine for Treatment of P. Vivax Malaria, Cruzeiro do Sul, Acre, Brazil The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Aug 01, 2018 Efficacy of 3 Regimens of Chloroquine and Primaquine for Treatment of P. Vivax Malaria, Cruzeiro do Sul, Acre, Brazil The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Chloroquine overdose is a life-threatening emergency and should be managed with cardio-respiratory and hemodynamic support, monitoring of potassium along with management of arrhythmias and convulsions, as necessary. A patient who survives the acute phase and is asymptomatic should be closely observed until all clinical features of toxicity resolve.