Please review the following URL and make sure that it is spelled correctly. Hydroxychloroquine (Plaquenil) is considered a disease-modifying anti-rheumatic drug (DMARD). Sudden withdrawal of hydroxychloroquine Plaquenil first dose Plaquenil can they be cut in half In 2003, a novel mechanism was described wherein hydroxychloroquine inhibits stimulation of the toll-like receptor TLR 9 family receptors. TLRs are cellular receptors for microbial products that induce inflammatory responses through activation of the innate immune system. Does that mean I have a suppressed immune system. Plaquenil probably won’t protect you from getting Covid-19, but it should make it less dangerous and shorten the lifespan. I hope that answers some questions. I have decided to take next week off and keep my kids home for the next week. It isn’t worth the risk, and I am lucky to have a. It alters your immune system, but as far as I know, it doesn't actually suppress it. Plus, if you have only been on it a month, it's probably not built up enough in your body to have much of an effect. I have actually been way HEALTHIER than ever since being on Plaquenil AND Methotrexate, which DOES suppress the immune system - go figure! It may prevent joint damage and reduce the risk of long-term disability. It can decrease the pain and swelling of arthritis. Plaquenil immune system Does plaquenil cause shingles, does it suppress the immune., Having lupus, and being on plaquenil. Does that mean I. Hydroxychloroquine hemodialysisAcid reflux and plaquenil The mechanism of action is thought to be anti-inflammatory, but Plaquenil also seems to reduce sensitivity to sunlight. It has also been noted recently that smoking reduces the effectiveness of Plaquenil in treating lupus, thus, smoking cessation should be instituted in all patients taking Plaquenil. More About Autoimmune diseases DERMATOMYOSITIS Plaquenil Use in Autoimmune Diseases. Does Plaquenil supress the immune system?. Treating Lupus with Anti-Malarial Drugs Johns Hopkins Lupus Center. However, it’s believed that this drug affects how your immune system works, which may be a benefit in lupus erythematosus and rheumatoid arthritis. Hydroxychloroquine side effects The mechanism is unknown. Combining telbivudine Tyzeka and hydroxychloroquine may increase the risk of unexplained muscle pain, tenderness, or weakness because both drugs cause such side effects. Hydroxychloroquine suppresses the immune system and should not be combined with drugs that also suppress the immune system or live vaccines. I doubt it is the Plaquenil affecting your immune system, but the actual Lupus itself as it can affects the white blood cells and lower them so we get every infection going. You need to speak to your rheumy for more clarification in your case.