Artemisinin Combination Therapies, or ACTs, are currently the frontline treatments against malaria. Although these treatments are working well in many parts of the world, there is serious concern that malaria parasites are once again developing widespread resistance to this vital treatment. Chloroquine side effects in pregnancy Taking plaquenil and sun exposure Malaria chemoprophylaxis chloroquine phosphate tablet 500 mg in the news Chloroquine dosing schedule Twelve years after the introduction of chloroquine in the 1940s, Plasmodium falciparum resistance to the drug developed and spread steadily throughout malaria-endemic regions. From Asia and South America, then into much of Africa, the once-efficacious medication has grown increasingly ineffective Wellems & Plowe, 2001 ; Wellems, 2002. Chloroquine phosphate or hydroxychloroquine sulfate Plaquenil can be used for prevention of malaria only in destinations where chloroquine resistance is not present see Chapter 2, Yellow Fever Vaccine & Malaria Prophylaxis Information, by Country. Prophylaxis should begin 1–2 weeks before travel to malarious areas. Malaria medicines are working well in many parts of the world, however, there is serious concern that malaria parasites are once again developing widespread resistance to antimalarial drugs. Description: An exception occurred while processing your request. As the threat of antimalarial drug resistance grows, there is increasing pressure to sustain the efficacy of existing treatments, develop alternative treatments, as well putting in place preventative measures such as bednets. Map of malaria regions chloroquine resistance Malaria Threat Map, Malaria - Chapter 4 - 2020 Yellow Book Travelers' Health. Chloroquine interactionsPlaquenil side effects weight lossPlaquenil during pregnancy categoryChloroquine working concentration Open the Malaria Threats Map; Global report on antimalarial drug efficacy and drug resistance. The Global report on antimalarial drug efficacy and drug resistance provides a comprehensive overview of drug efficacy and the resistance of malaria parasites to antimalarial medicines. WHO Global database on antimalarial drug efficacy and resistance. Malaria Drug Resistance Worldwide Antimalarial Resistance Network. Chloroquine Resistance in Plasmodium falciparum - microbewiki. Areas with Malaria Drug Resistance 2 Malaria Species 3 Recommended Chemoprophylaxis 4 Key Information Needed and Helpful Links to Assess Need for Prophylaxis for Select Countries; Namibia Present in the regions of Kavango East and West, Kunene, Ohangwena, Omusati, Oshana, Oshikoto, Otjozunjupa, and Zambezi. Rare cases in other parts of the. Drug-resistant malaria is spreading, but experts clash over its global risk. By Leslie Roberts Oct. 11, 2017, PM. In what scientists call a “sinister development,” a malaria parasite. Mizoram, a northeastern state in India, shares international borders with Myanmar and Bangladesh and is considered to be one of the key routes through which drug-resistant parasites of Southeast Asia enter mainland India. Despite its strategic location and importance, malaria epidemiology and molecular status of chloroquine resistance had not been well documented, and since chloroquine CQ.