Pattern of Retinopathy: Although the locus of toxic damage is parafoveal in many eyes, Asian patients often show an extramacular pattern of damage. Dose: We recommend a maximum daily HCQ use of 5.0 mg/kg real weight, which correlates better with risk than ideal weight. Hydroxychloroquine ok to stop Side affectss of plaquenil Abnormal hydroxychloroquine visual fields Hydroxychloroquine dyschromia Plaquenil is manufactured in only a 200 mg tablet The typical dosage is either 200 or 400 mg per day 200 mg daily puts anyone under 68 pounds at risk1 400 mg of Plaquenil daily puts anyone under 135 pounds at a higher risk for toxicity Therefore, 200mg of Plaquenil daily is going to be a safe dosage for virtually all adults13 SARCOIDOSIS TREATMENT GUIDELINES INTRODUCTION Sarcoidosis is a chronic inflammatory granulomatous dis-ease that primarily affects the lungs, although multi-organ involvement is common. The etiology of sarcoidosis is not clear; however, genetic and environmental factors probably play a role in the development and expression of the disease. Rheumatoid Arthritis. The action of hydroxychloroquine is cumulative and may require weeks to months to achieve the maximum therapeutic effect see CLINICAL PHARMACOLOGY. Initial adult dosage 400 mg to 600 mg 310 to 465 mg base daily, administered as a single daily dose or in two divided doses. In a small percentage of patients, side effects may require temporary reduction of the initial. Risk of Toxicity: The risk of toxicity is dependent on daily dose and duration of use. There are no similar demographic data for CQ, but dose comparisons in older literature suggest using 2.3 mg/kg real weight. Plaquenil oct guidelines My Take on New Ocular Screening Guidelines for Plaquenil., SARCOIDOSIS TREATMENT GUIDELINES How long does chloroquine itching lastWhy hair loss from plaquenilPlaquenil itchy skinChloroquine uk AAO revised guidelines. The AAO published dosing and screening recommendations for chloroquine and hydroxychloroquine in 2016, revising previous recommendations published in 2011. The current maximum daily HCQ dose recommended by the AAO is 5 mg/kg of real weight. The 2011 guidelines suggested a maximum dose of 6.5 mg/kg of ideal weight. Despite Plaquenil dosing recommendations, retinal toxicity.. Plaquenil Dosage Guide -. Plaquenil Oral Uses, Side Effects, Interactions.. Today it is recommended that every single person on Plaquenil get a visual field 10-2 test, plus one of the three other highly sensitive screening tests the FAF fundus autofluorescence imaging, the SD-OCT spectral domain optical coherence, or the multifocal electroretinogram mfERG,” Thomas says. While the latest recommendations do not require it, automated visual field VF testing and spectral domain optical coherence tomography SD-OCT are often done at this visit as well. Guidelines recommend a 10-2 threshold VF except for Asian patients where a wider angle test such as a 24-2 or 30-2 VF protocol will pick up the 50% that develop retinopathy outside the central 20 degrees of VF. The American Academy of Ophthalmology released an updated set of screening recommendations for hydroxychloroquine Plaquenil and chloroquine to account for the many studies that have shown the effects of these medications on the retina.