Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. 400 mg plaquenil at night Eye exam before plaquenil Can hydroxychloroquine cause vision changes PLAQUENIL hydroxychloroquine sulfate tablets is indicated for the treatment of rheumatoid arthritis, and discoid and systemic lupus erythematosus, in patients who have not responded satisfactorily to drugs with less potential for serious side effects. WebMD explains the causes, symptoms, and treatment of thrombocytopenia and ITP, conditions that cause you to have an abnormally low number of platelets in your blood. Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Plaquenil and thrombocytopenia Plaquenil Side Effects Common, Severe, Long Term -, Thrombocytopenia and ITP Causes, Symptoms, and Treatment Half life of chloroquine Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Hydroxychloroquine Plaquenil. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. Low platelet count thrombocytopenia Causes, treatment.. Keywords Immune thrombocytopenia, Plaquenil®, Platelets, Prednisone, T regulatory cells, Vitamin D. Introduction. Immune thrombocytopenic purpura ITP is thought to be an autoimmune disorder mediated by autoantibodies with no known etiology, and the incidence is approximately 2.5 per 100,000 persons per year. Find information about common, infrequent and rare side effects of Plaquenil Oral. Thrombotic thrombocytopenic purpura TTP is a rare blood disorder. In TTP, blood clots form in small blood vessels throughout the body. The clots can limit or block the flow of oxygen-rich blood to the body's organs, such as the brain, kidneys, and heart. As a result, serious health problems can.