It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. Plaquenil and prednisone during pregnancy Plaquenil long term use side effects I've just started taking Plaquenil again after a gap since last August, stopped because of an eye problem that was found to be not due to Plaquenil. I started feeling ill again in January and started Plaquenil two weeks ago. I was already a bit windy but I think this has increased, although I've never had a problem before. Common side effects may include headache, dizziness, ringing in your ears; nausea, vomiting, stomach pain; loss of appetite, weight loss; mood changes, feeling nervous or irritable; skin rash or itching; or. hair loss. For the Consumer. Continuing ringing or buzzing or other unexplained noise in the ears. feeling of constant movement of self or surroundings. irritability. nausea. nervousness. nightmares. sensation of spinning. shakiness and unsteady walk. uncontrolled eye movements. unsteadiness, trembling, or. For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too. Plaquenil side effects gas Will you have Abdominal bloating with Plaquenil - eHealthMe, Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses Weight loss from plaquenilChloroquine molecular formulaRheumatoid arthritis medication plaquenilDefine chloroquineHydroxychloroquine lysosome inhibitor RARE side effects. If experienced, these tend to have a Severe expression. Abnormal Liver Function Tests. Acute Liver Failure. Acute Pustular Eruptions On Skin. Bronchospasm. Decreased Blood Platelets. Decreased White Blood Cells. Common and Rare Side Effects for Plaquenil Oral. Hydroxychloroquine Side Effects Common, Severe, Long Term.. Plaquenil Side Effect - Horrible Flatulence?. Description and Brand Names. Drug information provided by IBM Micromedex US Brand Name. Plaquenil; Descriptions. Hydroxychloroquine is used to treat malaria. It is also used to prevent malaria infection in areas or regions where it is known that other medicines eg, chloroquine may not work. Plaquenil side effects. jessi19661 posted I was wondering if anone gets extreme gas intestinal from plaquenil? Plaq and some of my other meds say they cause stomach upset and diarrhea, but not gas. I am also on Keflex for sinus infection and strep throat, could it be the Keflex. I am very familiar with Plaquenil, and Plaq does cause some tummy discomfort at the start. It can cause loss of appetite, diarrhea, and accompanying gas and intestinal noises. You can get some OC Immodium AD to try and combat the lower bowel issues.