A, At the start of hydroxychloroquine sulfate treatment. B, Two years after starting treatment, a right paracentral scotoma appeared. When was chloroquin discovered Plaquenil toxicity screening recommendations Find patient medical information for Plaquenil Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Hydroxychloroquine is a well tolerated medication for various rheumatologic and dermatologic conditions. Its main side effects are gastrointestinal upset, skin rash, headache, and ocular toxicity. Within the eye, hydroxychloroquine negatively impacts the cornea, ciliary body, and retina. Chloroquine retinopathy, is a form of toxic retinopathy damage of the retina caused by the drugs chloroquine or hydroxychloroquine, which are sometimes used in the treatment of autoimmune disorders such as rheumatoid arthritis and systemic lupus erythematosus. This eye toxicity limits long-term use of the drugs. Morand EFMc Cloud PILittlejohn GO Continuation of long term treatment with hydroxychloroquine in systemic lupus erythematosus and rheumatoid arthritis. C, Three years after cessation of treatment, the scotoma regressed. Plaquenil visual field defect Recommendations on Screening for Chloroquine and., Hydroxychloroquine toxicity - EyeWiki Chloroquine autophagy protocolPlaquenil did not work for mePlaquenil naiseaIcd for starting plaquenil medicationSynthesis of chloroquine If you simply cannot get a visual field due to patient cooperation or attention, you can order an optic nerve OCT to follow the optic nerve head objectively though thinning does not always necessarily correlate to field loss. 2 Superior / inferior arcuate defect. The most common early to mid stage glaucomatous field. How to interpret visual fields 5 most common patterns - EyeGuru. Chloroquine retinopathy - Wikipedia. How to Succeed in Plaquenil Screenings. Central threshold automated visual fields with a white target • Subtle, repeatable visual field defectsshould be taken seriously and are an indication to do objective testing At least one of the following objective tests should be performed during routine screening if available19 Diagnosis Hydroxychloroquine-induced retinal toxicity Discussion. Chloroquine CQ and hydroxychloroquine Plaquenil HCQ have been used for many years, initially for the treatment of malaria but now more commonly for the treatment of inflammatory diseases such as rheumatoid arthritis and lupus 1. Summary Visual field defect is found among people who take Plaquenil, especially for people who are female, 60+ old, have been taking the drug for 10+ years, also take medication Methotrexate, and have Osteoporosis.