Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Plaquenil and excessive sweating Quinine in generic plaquenil I to have been taking plaquenil for at least 6 to 8 months not sure a lil lupie lol anyway and i do feel a difference in my eyes plus my liver enzymes are up i believe that the highest is 47 and mines is 48 the doc says not dangerously high but we need to keep an eye on it. im not sure but i thought that the enzymes were up cuz of the prednisone but now ill have to ask the doc. i too want. Plaquenil can damage the retina of the eye. This can lead to blindness. This problem is most common when high doses are taken for a long time. If you will be taking Plaquenil for a while, it is recommended to have a thorough eye exam before starting it and every three months while taking it. Plaquenil and Liver function test abnormal - from FDA reports Summary Liver function test abnormal is found among people who take Plaquenil, especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months, also take medication Enbrel, and have Osteoporosis. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Plaquenil liver enzymes Aspirin, hydroxychloroquine, and hepatic enzyme., Plaquenil Warnings and Precautions Mefloquine hydrochloride chloroquinePlaquenil farmacias del ahorroPlaquenil dizzinessPlaquenil and lithiumPlaquenil warnings vision Elevated liver enzymes are a common problem in some patients being treated with hydroxychloroquine, such as patients with lupus. However, as a general rule, hydroxychloroquine is not associated with an elevation in liver enzymes when used to treat autoimmune and rheumatologic diseases. Hydroxychloroquine Plaquenil Success, Reviews and Side.. Will you have Liver function test abnormal with Plaquenil.. Plaquenil Side Effects Common, Severe, Long Term -. Plaquenil has never raised my liver enzymes and I have been on it for six years. The only time my ALT and AST were elevated when I was taking too much iron supplements for my anemia. Once I stopped those, the enzymes went back to normal. Elevated liver enzymes may indicate inflammation or damage to cells in the liver. Inflamed or injured liver cells leak higher than normal amounts of certain chemicals, including liver enzymes, into the bloodstream, which can result in elevated liver enzymes on blood tests. The specific elevated liver enzymes most commonly found are Plaquenil was originally approved by the Food and Drug Administration FDA in 1955. Plaquenil Warnings. Before taking Plaquenil, tell your doctor if you have or have ever had Liver disease.