So far I have no more energy than when I first started and has developed neuropathy which I have just found out from Web MD that this neuropathy is one of the side effects of this med! Saying that by stopping this it would take another 6 months to build up the benefit. There are other meds that can help with what you are experiencing, and if your doctor didn't address that then I would seek out a second opinion... Please don't stop your plaquenil until you are sure it is the right thing to do and in your best interest. Chloroquine causes itch mechanism Fluoroquinolones and chloroquine In general, one should consider withdrawal of the medication three or four days prior to surgery. Hydroxychloroquine is a less commonly utilized disease modifying anti-rheumatic medication. It is an anti-malarial medication. There is no indication that Plaquenil requires discontinuation in the perioperative period. In Conclusion This phase I / II trial studies the side effects and best dose of hydroxychloroquine when given together with palbociclib and letrozole before surgery in treating participants with estrogen receptor positive, HER2 negative breast cancer. Hydroxychloroquine is a substance that decreases immune responses in the body. The toxicity profile of hydroxychloroquine contributes little risk in stopping or continuing use during surgery since individuals are able to recover quickly with this medication after outpatient operations 20,21. It appears to be safe treatment for RA in the presence of elective surgery with renal function monitoring 17. Plaquenil is a 6-weeker as far as the benefits are concerned, but it would be more dangerous to stop if you spend a lot of time outside and if this were the summer. Or maybe another doctor if you're not comfortable w/your current one. Do you need to stop hydroxychloroquine before surgery Hold the immunomodulators for surgery? Maybe yes, maybe no., Hydroxychloroquine, Palbociclib, and Letrozole before Surgery in. Plaquenil weight gain at 400mgQuinoric hydroxychloroquine side effectsChloroquine and arthritisAutophagy flux kroemer chloroquineHow to say plaquenil The main goal of this research study is to determine whether treating patients with renal cell cancer with hydroxychloroquine before surgery can make the cancer easier to kill. Another goal is to see how the study drug affects the body's immune cells which fight cancer cells. Study of Hydroxychloroquine Before Surgery in Patients With Primary.. The Safety of Elective Surgery with Concurrent Use of Immunosuppressants. Plaquenil Uses, Dosage & Side Effects -. If your rheumatoid arthritis symptoms do not improve, or if they worsen, stop taking the drug and call your doctor. Once you and your doctor are sure the drug works for you, do not stop taking hydroxychloroquine without talking to your doctor. Symptoms of rheumatoid arthritis will return if you stop taking hydroxychloroquine. Evidence for this comes from a randomized clinical trial in which patients with rheumatoid arthritis RA were assigned to either continue on methotrexate MTX or suspend taking it for 2 weeks before and 2 weeks after surgery. The study also contained a control of patients with RA who were not on MTX Ann. Rheum. Dis. Surgery while taking Plaquenil? 996 conversations on the web about experiences with taking Plaquenil before or after having a Surgery - Page 5. My Dr. wanted me to stop the Plaquenil due to the change in my hearing, and now I've been on Methotrexate for a couple of years. The tinnitis is still.