Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Hydroxychloroquine pregnancy class Hydroxychloroquine scleroderma As long as you see your eye care professional regularly, you can feel confident that the plaquenil is safe. If any changes occur in the retina, a dye test is ordered to take pictures of the retina to document any changes noted. Plaquenil is used in the treatment of sarcoidosis but its main use is in the treatment of malaria. One of the side effects of taking the drug is that it affects eye sight, and eye tests, especially field of vision tests need to be done every six months. Jun 13, 2019 Some diseases treated with Plaquenil include Lupus, which causes fever, rashes, skin problems, and other symptoms. Rheumatoid arthritis, a condition that causes pain and swelling in the joints of your hands and feet. Sjögren’s syndrome, which causes dry eyes and dry mouth. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Plaquenil and eye pain Plaquenil Uses, Dosage & Side Effects -, Plaquenil Withdrawal – Life As An Anomaly Plaquenil maculopathy mechanismsHydroxychloroquine retinitis pigmentosaHydroxy chloroquine dosage for rheumatoid arthritis Beyond Plaquenil Other Drugs, Other Problems. If you’re looking for a comprehensive assessment of drug reactions that relate to the eye, Dr. Fraunfelder and his father, Frederick T. “Fritz” Fraunfelder, MD, along with Wiley A. Chambers, MD, literally wrote the book. 3 “So many drugs can cause ocular side effects that if you’re trying to make a point about which drugs to watch out. Rx Side Effects New Plaquenil Guidelines and More.. What Is Plaquenil? - American Academy of Ophthalmology. Protecting your eyesight when taking Plaquenil Lupus.. Talk to your doctor about this, but my guess is that the Plaquenil is not doing anything to cause the pain, but rather that it is not doing enough to prevent it. It sounds like your RA has probably gotten a bit out of control, relative, to your current treatment, and Plaquenil is not a particularly potent drug when it comes to managing joint pain. Side Effects Nausea, stomach cramps, loss of appetite, diarrhea, dizziness, or headache may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Remember. HCQ is cleared by the kidneys and thus renal disease increases the risk of toxicity. Therefore, both dosage and screening frequency may need to be adjusted. Tamoxifen use used in breast cancer treatment increases the risk of toxicity approximately 5 fold 8. The mechanism of this linkage is not understood.