Plaquenil dosage maculopathy

Discussion in 'Plaquenil' started by vadim_crow, 25-Feb-2020.

  1. ph0en1x User

    Plaquenil dosage maculopathy


    Pattern of Retinopathy: Although the locus of toxic damage is parafoveal in many eyes, Asian patients often show an extramacular pattern of damage. Dose: We recommend a maximum daily HCQ use of 5.0 mg/kg real weight, which correlates better with risk than ideal weight.

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    If a patient is on a dose that exceeds 5 mg/kg/day of real body weight, the prescribing physician should be contacted to ensure that the dose can be adjusted and medical risks are managed. The risk of plaquenil-induced toxic maculopathy is associated with a cumulative dose level of 1,000 grams and it usually takes 5-7 years for patients on the standard dose of 250-400 milligrams per day to reach that level. 2 Based on a dose of 200 milligrams per day for the past twenty years. Avoid coadministration of hydroxychloroquine and doxorubicin if possible. If not possible, closely monitor for increased side effects of doxorubicin including myelosuppression and cardiotoxicity. Dronedarone Severe Dronedarone administration is associated with a dose-related increase in the QTc interval. The increase in QTc is approximately 10 milliseconds at doses of 400 mg twice daily the FDA-approved dose and up to 25 milliseconds at doses of 1600 mg twice daily.

    Risk of Toxicity: The risk of toxicity is dependent on daily dose and duration of use. There are no similar demographic data for CQ, but dose comparisons in older literature suggest using 2.3 mg/kg real weight.

    Plaquenil dosage maculopathy

    Hydroxychloroquine Dosage Guide with Precautions -, Plaquenil-Induced Toxic Maculopathy - Decision-Maker PLUS

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  6. Jan 03, 2020 Initial adult dosage 400 mg to 600 mg 310 to 465 mg base daily, administered as a single daily dose or in two divided doses. In a small percentage of patients, side effects may require temporary reduction of the initial dosage.

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    Several risk factors may increase the likelihood of retinal toxicity from Plaquenil such as, age of greater than 60 years, daily dose more than 6.5 mg/kg; use of the drug more than 5 years, obesity, preexisting retinal disease and, renal or liver failure. What is the dosage for hydroxychloroquine Plaquenil? The usual adult dose for treating malaria is 800 mg initially, followed by 400 mg 6-8 hours later and then 400 mg at 24 hours and 48 hours. The dose for malaria prevention is 400 mg every week starting 1 or 2 weeks before exposure and for 4 weeks after leaving the high risk area. Plaquenil is manufactured in only a 200 mg tablet The typical dosage is either 200 or 400 mg per day 200 mg daily puts anyone under 68 pounds at risk1 400 mg of Plaquenil daily puts anyone under 135 pounds at a higher risk for toxicity Therefore, 200mg of Plaquenil daily is going to be a safe dosage for virtually all adults13

     
  7. wServer XenForo Moderator

    Plaquenil is the brand name for the prescription drug hydroxychloroquine. Drugs That Can Interfere With Plaquenil Plaquenil Hydroxychloroquine - Side Effects, Dosage. Plaquenil Oral Uses, Side Effects, Interactions.
     
  8. cashersmart Well-Known Member

    Plaquenil Hydroxychloroquine Side effects, Images, Uses. Feb 19, 2020 Take hydroxychloroquine with a meal or a glass of milk. To prevent malaria Start taking the medicine 2 weeks before entering an area where malaria is common. Continue taking the medicine regularly during your stay and for at least 8 weeks after you leave the area.

    Taking Plaquenil for Rheumatoid Arthritis