It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. Does plaquenil affect blood pressure Hydroxychloroquine and caffeine This means many people taking Plaquenil for RA are taking a dose of 400mg a day or higher. Pigment deposits in the retina can cause vision changes, according to Steven Ofner, M. D. of Eugene Oregon Eye Care. Signs of retinal damage include blurry or distorted vision, flashes of light or floaters, or loss of night vision. The Risk of Retinal Toxicity with Plaquenil. Posted on Fri. Early detection of the maculopathy is of critical importance to discontinue Plaquenil in order to stop or slow retinal damage. Unfortunately, clinically evident early structural changes can be subtle and usually preceded by abnormalities in functional tests such as visual field. Vision risks. Hydroxychloroquine is dosed according to body weight. The American Academy of Ophthalmology AAO currently defines an overdose of hydroxychloroquine as more than 5.0 milligrams mg per kilogram kg of body weight 1 kg equals 2.2 pounds or more than 400 mg a day. For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too. Plaquenil eye damage Plaquenil - Colorado Springs Eye Clinic, The Risk of Retinal Toxicity with Plaquenil Diluting chloroquine for in vivo treatmentsCauses for plaquenil to stop workingHow to get on hydroxychloroquinePlaquenil 400 mg bugiardino Plaquenil and Eye Problems. Plaquenil can cause serious vision problems that aren't always reversible. Tell your doctor immediately if you notice any changes in vision or if you've ever had vision. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. Wrong Hydroxychloroquine Dose Is Common, Putting Eyes at.. What can Hydroxychloroquine Plaquenil do to my eyes?. A risk factor for Plaquenil hydroxychloroquine retinotoxicity is a daily dose that exceeds 5.0 mg of drug per kg of body weight. The tool on the right simply calculates this threshold based on a ppatient’s real body weight. The overall prevalence of toxicity in this group was 7.5% with a wide variation in daily dose and duration of use. Beyond this point the risk increases sharply to 20% after 20 years 7. The risk is lower with a lower dose however there is no true safe dosage for longer duration of use. Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more.