They are most common among people with weak immune systems. People with certain health conditions may need to take medications with side effects that can weaken your immune system and put you at risk for fungal infections. Is plaquenil an anti inflammatory Dwarflionfish and chloroquine Chloroquine long term side effects Plaquenil itself probably does not have a direct affect on your immune system - it is a DMARD and is not considered to be an immunosuppressant. However, many with active autoimmune diseases feel that they are not succeptible to many of the common viruses that they are exposed to - somewhat of a silver lining. Today, Plaquenil and other antimalarials are also used to treat and help prevent symptoms caused by certain autoimmune diseases such as rheumatoid arthritis RA, systemic lupus erythematosus, and discoid lupus, even though these diseases are not caused by malaria parasites. I doubt it is the Plaquenil affecting your immune system, but the actual Lupus itself as it can affects the white blood cells and lower them so we get every infection going. You need to speak to your rheumy for more clarification in your case. Fungal infections can range from mild to life-threatening. Specifically, corticosteroids and TNF (tumor necrosis factor) inhibitors are two types of medications that can increase your chances of getting a fungal infection. How does plaquenil work on the immune system Hydroxychloroquine Plaquenil Side Effects & Dosage for., Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus How to prescribe chloroquineHydroxychloroquine interactions in dental treatment All work by suppressing the immune system. If he wants this type of drug he can try to balance control of his autoimmune disease with the risk of infection. What I mean is He might want to consider taking a lower dose of Plaquenil. This won't suppress his immune system quite as much but it also won't completely control his Sjogrens. Do either hydroxychol/Plaquenil put you at risk for.. Plaquenil and immune system Lupus Forums at The Lupus Site. Medications that Weaken Your Immune System and Fungal.. Aug 02, 2010 Plaquenil works by suppressing the immune system. Unfortunately you can't tell it to attack just the germs so you suppress all of its function to spare your healthy tissue- in your husband's case, his eyes, mouth, throat. NOTE Plaquinil and hydroxychloroquine are essentially the same drug. The same effects should be expected from both drugs. 2. No, his immune system should not be forever compromised. Plaquenil is a disease-modifying drug originally developed to treat malaria. Plaquenil is believed to work by interfering in communication between the cells of the immune system. How do I take it? You may need to see an ophthalmologist not an optometrist for a checkup before beginning to take Plaquenil. Plaquenil is prescribed as a disease-modifier, in other words, to decrease pain, decrease swelling, and prevent joint damage and disability. It is not known how Plaquenil works but researchers believe that Plaquenil interferes with communication between cells within the immune system. Ultimately, it is thought to block proinflammatory pathways.